Negative Pressure & Heat

Pain relief from the palm of your hand
Whole-body pain relief and improved circulation for better health

Energy

Circulation

Repair

Relief

Balance

AVACEN® stands for Advanced VAscular Circulation ENhancement

AVACEN is a noninvasive, drug-free, over-the-counter (OTC) heat therapy system indicated for: 1) temporary relief of minor muscle pain, joint pain, and stiffness 2) temporary relief of joint pain associated with arthritis, muscle spasms, and minor strains and sprains 3) muscular relaxation, and 4) temporary increase of local circulation where applied. FDA 510(k) Clearance – Indications for use

What is AVACEN®?

AVACEN® is a noninvasive, over-the-counter (OTC) heat therapy system indicated for:

  • Minor muscle pain, joint pain, and stiffness
  • Joint pain associated with arthritis
  • Muscle spasms
  • Minor strains and sprains
  • Muscle relaxation
  • Temporary increase of local circulation 

How does AVACEN® work?

AVACEN® products are intended to improve local circulation in muscle tissue in as little as 20 minutes of treatment, facilitating and improving microcirculation throughout the entire body. Since 2009, the benefits of AVACEN devices have impacted thousands of people worldwide, with over 25 million treatments to date. AVACEN is an FDA Cleared Class II medical device that is safe, effective, noninvasive and easy to use.

Negative Pressure & Heat Courses

Functional Longevity Method & Biotekna Overview

This foundational module introduces the Functional Longevity Method and the scientific ecosystem behind it. Learn the core principles of multi-system assessment (brain, ANS, vascular, metabolic, and ECM), how the method integrates advanced technologies, and the science, history, and global research behind Biotekna.

Integrated Systemic Assessments (GHI, OSO, PH)

Integrate Biotekna’s GHI, OSO, and PH reports into one view of systemic regulation: cell vitality, stress load, metabolic and inflammatory status, body composition patterns, and 5-year multisystem risk trends from large AI datasets.

Cellular Repolarization & Biofeedback (RegMatEx)

Explore how RegMatEx restores membrane potential and extracellular ionic balance through electrodermal biofeedback. Understand electrical dysregulation in chronic stress, fatigue, inflammation, and metabolic dysfunction.

ECM Remodeling & Functional Feedback (TomEEx)

Learn how TomEEx assesses extracellular matrix readiness, regulatory dynamics, and energy availability, and how its 10 Hz polarized microcurrent stimulation triggers targeted ECM remodeling. Understand how these changes influence recovery, inflammation, and overall physiological regulation.

ANS Regulation & Respiratory Biofeedback (PPG Stress Flow)

Master the PPG Stress Flow system to evaluate autonomic balance, vascular dynamics, breathing patterns, and stress physiology. Learn respiratory biofeedback techniques to modulate SNS/PNS activity, improve HRV, and restore autonomic stability.

Body Composition & Tissue Health (BIA-ACC)

A comprehensive training on advanced body composition metrics beyond fat and muscle. Learn how to interpret tissue quality, inflammation, metabolic balance, and structural resilience through the BIA-ACC system.

The AVACEN® Treatment Method

Over the last 2 years, AVACEN Medical® has been awarded 5 U.S. and 9 International patents for its unique apparatus and methods that support its innovative medical process called The AVACEN® Treatment Method (ATM).

Key Features of AVACEN®

Vacuum Chamber

When the hand, enclosed in a special patented mitt, is placed inside the vacuum chamber, negative pressure and heat are applied to safely increase the temperature and blood volume flowing through high volume arteriovenous anastomoses (AVAs). It is important to note that the application of heat without negative pressure is ineffective.

Microcirculation

An increase in microcirculation enhances oxygen delivery and nutrition to the skeletal muscles while carrying away carbon dioxide and waste. The result – healthier, more relaxed muscles throughout the entire body.

Heat Infusion

Infusing heat into the circulatory system reduces blood thickness (viscosity) and increases microcirculation. Thinner blood facilitates more efficient flow through the skeletal muscles on its route to the smaller vasodilated capillaries (microvascular circulation) which the body uses to radiate the excess ATM produced heat.

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Educational Resource Notice:

This page provides research summaries and background reading for educational purposes only. It is not AVACEN labeling and is not intended to promote uses beyond AVACEN’s FDA-cleared indications. Some studies summarized here involve specific clinical populations and outcomes; these summaries do not establish that AVACEN is cleared to diagnose, treat, cure, or prevent any disease. Individual results vary. Consult a qualified healthcare professional for medical advice.