Highlights
- A single 20-minute AVACEN session (left hand) was followed by a rapid increase in peripheral circulation markers, led by a +113% rise in Bilateral Flow Gain.
- The perfusion index increased by 83%, shifting peripheral perfusion from moderate to good immediately after the session.
- Cerebral circulation also showed a strong response, with the HEG-derived CBF ratio increasing 94% right after the session.
- Several effects were still evident 30 minutes later, including left-side BFG remaining ~12% above baseline and CBF ratio remaining 32% above baseline.
People often describe feeling “warmer,” “more relaxed,” or “more clear-headed” after a wellness session — but it’s even more compelling when there are numbers to look at. Below is a short case snapshot showing what happened when one individual completed a single 20-minute AVACEN session applied to the left hand, with objective measurements collected before and after using Biotekna’s non-invasive PPG and HEG devices. This is not a clinical trial. It’s a real-world look at immediate response patterns — measured in real time.
The case at a glance
A 54-year-old male completed a 20-minute AVACEN session on the left hand. Measurements were taken at three timepoints: baseline (pre-session), immediately after the session, and again 30 minutes later.
Biotekna devices were used to capture both peripheral and cerebral circulation-related markers, including Bilateral Flow Gain (BFG), perfusion index, pulse transit time (PTT), and an HEG-derived cerebral blood flow metric reported as a CBF ratio.
What changed right away
The most striking changes appeared immediately after the session — especially on the treated side.
Peripheral circulation markers (PPG)
Bilateral Flow Gain on the left side increased from 196.8 at baseline to 419.7 immediately after the session, a +113% increase. The right side also increased, from 153.5 to 195.4 (+27%), but the strongest response was clearly on the treated side.
The perfusion index — a marker commonly used to reflect peripheral perfusion quality — rose from 1.8% at baseline to 3.3% immediately after the session, an +83% increase. In practical terms, this moved the reading from moderate peripheral perfusion to good peripheral perfusion, which is exactly the type of shift many people hope to see when targeting circulation and comfort.
Pulse transit time (PTT) started in an already optimal range at 126.8 ms and increased to 147.0 ms immediately after the session (+16%).
Cerebral circulation marker (HEG)
Cerebral blood flow (reported as CBF ratio) increased from 217 at baseline to 421 immediately after the session, a +94% increase — a very large acute change for a single, short session.
Did the effect last? (30-minute follow-up)
The follow-up measurement 30 minutes later showed that several markers remained above baseline — suggesting the response wasn’t just a brief, “in-the-moment” fluctuation.
On the left side, BFG remained above baseline at 220.5 (approximately +12% vs baseline). Perfusion index also stayed higher than baseline at 2.0%. Cerebral blood flow (CBF ratio) remained elevated as well, measuring 287 — approximately +32% above baseline.
Not every metric stayed elevated in the same direction on both sides (for example, the right-side BFG at 30 minutes was below baseline), which is a helpful reminder that short-term physiology can be dynamic and individualized. But the overall pattern remained encouraging: the treated side and the cerebral blood flow marker showed sustained elevation compared with baseline.
Why this is exciting
What makes this case interesting is not just that numbers changed — it’s the shape of the response.
A short session applied to one hand was followed by a strong immediate rise in markers associated with peripheral circulation, alongside a major increase in a cerebral blood flow ratio metric. Even 30 minutes later, several values were still higher than baseline. In other words, this wasn’t only an “instant” effect that disappeared as soon as the session ended.
For people exploring wellness tools to support relaxation, circulation, and overall performance, this kind of measurable response is exactly what “a good session” often looks like on objective monitoring.
The key results
- BFG (left/treated side): 196.8 → 419.7 immediately after (+113%); 220.5 at 30 min (+12% vs baseline)
- Perfusion index: 1.8% → 3.3% immediately after (+83%); 2.0% at 30 min (still above baseline)
- Cerebral blood flow ratio (HEG): 217 → 421 immediately after (+94%); 287 at 30 min (+32% vs baseline)
Figure 1. Immediate changes in peripheral perfusion and cerebral blood flow markers following a single 20-minute AVACEN session. Bar graphs illustrate non-invasive measurements collected at baseline (Before) and immediately after a 20-minute AVACEN session in a 54-year-old male. Bilateral Flow Gain (left side) and perfusion index were assessed using Biotekna PPG, while cerebral blood flow is shown as an HEG-derived CBF ratio. Red percentages above each panel indicate the relative increase from baseline.
Final takeaway
This single-session case snapshot captured a strong, immediate physiological shift — most notably on the treated side — along with a substantial rise in a cerebral blood flow marker that remained elevated at 30 minutes. In practical terms, an increase in peripheral perfusion can be consistent with improved delivery of oxygen and nutrients to tissues and a greater sense of warmth, comfort, or “circulatory ease” in the extremities for some individuals. Likewise, a short-term rise in a cerebral blood flow marker may align with experiences people often describe after sessions such as feeling more alert, mentally “lighter,” or more cognitively engaged — though these subjective effects were not formally assessed here. While individual responses can vary, this case provides a clear, encouraging example of how one brief session can be followed by measurable, near-term changes in circulation-related metrics, with signals that can persist beyond the end of the session.
Link to full report: Read here