Explore the cutting edge of health and wellness through our Integrative Research portal, where we dive into the latest findings and foster discussions that shape the future of integrative medicine.
Highlights Red and near-infrared PBM consistently influence mitochondrial ATP production. Cytochrome c oxidase and ATP synthase are key photobiological targets. ATP increases depend on wavelength, fluence, pulse structure, and tissue...
Highlights Green laser PBM (≈505–532 nm) has been widely studied, but mostly in ablative or photocoagulative contexts. Evidence for direct activation of mitochondrial ETC complexes by green light remains limited....
Highlights PBM effects on mitochondria are wavelength-, dose-, and time-dependent. Cytochrome c oxidase (Complex IV) is a primary photoreceptor for red and NIR light. Different wavelengths can stimulate or inhibit...
Highlights He–Ne laser therapy induced repigmentation in patients with segmental vitiligo. Significant repigmentation occurred in approximately 60% of treated patients. Cutaneous microcirculation abnormalities improved following therapy. Sympathetic nerve function showed...
Highlights Pulsed transcranial PBM improved cognitive performance in veterans with chronic TBI. Regional cerebral blood flow increased in most participants. Effects were observed even years after the original brain injury....
Highlights Home-based PBM improved cognition and behavior in patients with dementia. Cerebral perfusion and functional connectivity increased. The protocol combined transcranial and intranasal PBM. Treatments were well tolerated with no...
Highlights Transcranial PBM increased cerebral blood flow and oxygenation. Improvements were observed in memory, planning, and processing speed. Depressive symptoms were reduced following PBM. Effects were more pronounced in the...
Highlights In a randomized, double-blind, sham-controlled study, transcranial near-infrared stimulation (tNIRS) was associated with a significant reduction in anxiety symptoms. Improvements were observed right after treatment and were still present...
Highlights Laser needle acupuncture was associated with measurable changes in brain-related signals, including cerebral blood flow and fMRI activation patterns. Because the stimulation is typically imperceptible, researchers can run true...
Highlights Diabetic peripheral neuropathy (DPN) involves neurovascular dysfunction and chronic pain. Low-level laser therapy (LLLT) improved nerve conduction and microcirculation. Laser-treated patients experienced greater pain reduction than controls. Improvements were...