Transcranial Photobiomodulation in Cognitive Rehabilitation After Traumatic Brain Injury
Highlights Transcranial PBM increased cerebral blood flow and oxygenation. Improvements were observed in memory, planning, and processing speed. Depressive symptoms were reduced following PBM. Effects were more pronounced in the left hemisphere. PBM was safe and feasible in chronic severe TBI patients. Background Traumatic brain injury (TBI) often leads to long-term cognitive and psychological […]
Transcranial Near-Infrared Stimulation Relieves Anxiety Symptoms
Highlights In a randomized, double-blind, sham-controlled study, transcranial near-infrared stimulation (tNIRS) was associated with a significant reduction in anxiety symptoms. Improvements were observed right after treatment and were still present at 2, 4, and 8 weeks follow-up. Stimulation targeted the left dorsolateral prefrontal cortex (DLPFC), a region involved in attention and emotional regulation. Brain network […]
How Laser Needle Acupuncture May Modulate Brain Function
Highlights Laser needle acupuncture was associated with measurable changes in brain-related signals, including cerebral blood flow and fMRI activation patterns. Because the stimulation is typically imperceptible, researchers can run true double-blind, placebo-controlled studies more easily than with traditional needles. Brain measurements suggested effects in areas linked to visual processing and attention/cognition. The session was non-invasive […]
Low-Level Laser Therapy and Diabetic Peripheral Neuropathy: A Promising Approach for Neurovascular Function
Highlights Diabetic peripheral neuropathy (DPN) involves neurovascular dysfunction and chronic pain. Low-level laser therapy (LLLT) improved nerve conduction and microcirculation. Laser-treated patients experienced greater pain reduction than controls. Improvements were observed in both neural and vascular parameters. LLLT was safe and well tolerated. Why this matters DPN is a common and debilitating complication of […]
Transcranial LED Therapy Improves Cerebral Blood Flow in Elderly Women
Highlights In a study of healthy older women, transcranial LED light therapy was linked to increases in brain blood-flow speed in specific arteries. The clearest changes were seen in the left middle cerebral artery and the basilar artery. Measures of vascular resistance decreased, suggesting blood vessels may have been functioning more efficiently during the assessment. […]
Complete Remission of Chronic Low Back Pain Following Photobiomodulation Therapy
Highlights In this case report, a middle-aged adult with persistent low back pain reported a complete reduction in pain after a short PBM treatment series. Treatment used dual-wavelength red + near-infrared laser light applied over the low back muscles. Pain and disability scores improved to zero by the end of care. The patient also reported […]
What Is Photobiomodulation?
Highlights Photobiomodulation (PBM) is a non-thermal light therapy using red and near-infrared wavelengths. PBM acts primarily at the mitochondrial level, especially on cytochrome c oxidase. The therapy modulates ATP production, oxidative stress, inflammation, and nitric oxide signaling. PBM has demonstrated neuroprotective, analgesic, and tissue-repair effects. A wide range of neurological, musculoskeletal, and regenerative applications have […]
Photobiomodulation Therapy for Shoulder and Neck Pain
Highlights Shoulder and neck pain are leading causes of musculoskeletal disability. PBM therapy shows consistent benefits for pain relief and functional improvement. Infrared wavelengths were most commonly used across clinical studies. PBM was found to be safe and non-invasive. Protocol variability highlights the need for standardized clinical trials. Scope of the Review This comprehensive […]
Low-Level Laser Therapy for Carpal Tunnel Syndrome: A Pilot Study
Highlights Carpal Tunnel Syndrome (CTS) causes pain, numbness, tingling, and reduced hand strength. A single session of low-level laser therapy (LLLT) produced immediate and short-term symptom relief. Significant improvements were observed in pain, sensory symptoms, grip strength, and functional scores. The intervention used a Class 3B dual-wavelength laser (red + infrared). Findings support PBM as […]
Class 3B Laser PBM for Pain Relief: A Dose-Dependent Effect
Highlights In a mouse model of inflammatory pain, Class 3B laser photobiomodulation (PBM) reduced pain sensitivity in a dose-dependent The strongest and most consistent effects were seen at mid-range doses (rather than the lowest or highest). Repeated daily sessions helped maintain pain reduction over time. Swelling (edema) did not meaningfully change, suggesting PBM may primarily […]