Highlights
- Two pilot studies in adults aged 60–83 explored the effects of daily NanoVi Exo® sessions on sleep, mood, fatigue, and physiological resilience.
- Participants reported better sleep quality, including fewer awakenings and less daytime sleepiness, with statistically significant improvements in sleep disturbance scores.
- Stress, anxiety, and depressive symptoms declined, while emotional well-being and social participation improved across the 30-day period.
- Fatigue and pain interference decreased, and participants noted enhanced physical function and vitality.
- Physiological trends pointed to improved heart rate variability and brain oxygenation, suggesting greater autonomic balance and recovery capacity.
- These preliminary results highlight NanoVi Exo®’s potential to support healthy aging naturally and non-invasively, warranting larger, controlled studies.
Introduction
Aging is often accompanied by changes such as poorer sleep quality, greater fatigue, increased stress, and reduced physiological resilience. While these changes are a natural part of life, research continues to explore approaches that may help support overall well-being in older populations. The NanoVi Exo® is a wellness device designed to support the body’s natural repair and recovery processes.
Two recent pilot studies conducted by Scientifica Consulting, explored whether NanoVi Exo® sessions could influence key aspects of wellness, including sleep, mood, fatigue, and physiological resilience, in adults aged 60 and older.
Study Observations
Across the two exploratory studies, a small group of older adults (n = 15, ages 60–83 years) participated in daily NanoVi Exo® sessions lasting 15–20 minutes. Participants completed validated questionnaires on sleep, mood, fatigue, pain, and physical function. In some cases, physiological measures such as heart rate variability and cerebral blood flow were also assessed using non-invasive devices.
✅ Key Observations
Sleep Quality
Participants reported falling asleep more easily, experiencing fewer nighttime awakenings, and feeling less sleepy during the day. Questionnaires showed statistically significant improvements in sleep disturbance and sleep-related problems.
Emotional Well-Being
Reductions in stress, anxiety, and depressive symptoms were observed, with some measures reaching statistical significance. Participants also reported improvements in emotional well-being and social participation.
Fatigue, Pain, and Physical Function
Fatigue scores improved progressively, while participants also reported reductions in pain interference and intensity, along with perceived improvements in physical function.
Physiological Trends
While not statistically significant, trends suggested favorable changes in heart rate variability and cerebral blood flow, pointing toward potential benefits for autonomic balance and oxygenation.
Conclusion
Together, these pilot studies suggest that daily NanoVi Exo® sessions may support better sleep, reduced fatigue, and improved emotional well-being in older adults, alongside promising trends in physiological resilience. While these results are preliminary and based on small study groups, they highlight the potential for further research in larger, controlled trials.
These studies were conducted using the NanoVi Exo® device, manufactured by Eng3 Corporation
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Figure 1. Figure 1. Changes in heart rate variability parameters (SDNN, RMSSD, and Total Power) before and after 30 days of daily NanoVi Exo® sessions. Results indicate enhanced autonomic regulation and recovery capacity following consistent use.
Figure 2. Improvements in self-reported sleep parameters at midpoint and after 30 days of daily NanoVi Exo® sessions.
Figure 3. Reductions in Depression, Anxiety and Stress at midpoint and after 30 days of daily NanoVi Exo® sessions.
Figure 4. Reduction in Fatigue scores at midpoint and after 30 days of daily NanoVi Exo® sessions.
Link to full paper: Read here