Highlights
- Daily NanoVi Exo® sessions showed measurable wellness gains. Over 30 days, a 61-year-old participant experienced better sleep quality, less fatigue, and higher brain blood flow with just 20 minutes of daily use.
- Fatigue and sleep improved most dramatically. Sleep quality scores improved by up to 64%, and total fatigue dropped by 60%, suggesting enhanced recovery and restfulness.
- Brain oxygenation and circulation increased. Cerebral blood flow rose by an impressive 88%, hinting that daily NanoVi Exo® use may help support neurovascular function.
Could daily, non-invasive wellness sessions help improve sleep, reduce fatigue, and boost brain blood circulation?
This 30-day case study of “C.S.”, a 61-year-old female, provides encouraging evidence.
What is the NanoVi Exo®?
The NanoVi Exo® delivers humidified, activated air to support cellular repair and help the body recover from oxidative stress. The aim: promote relaxation, enhance recovery, and improve overall well-being without invasive methods.
The Participant & Protocol
- Age: 61 years
- Routine: 20 minutes daily with the NanoVi Exo® for 30 days
- Assessments:
- Self-reported questionnaires: MOS Sleep Scale, DASS-21, Chalder Fatigue Scale, PROMIS-29
- Physiological measures: Hemodynamic brain monitoring via HEG (Biotekna, Italy)
- Measurements at baseline, day 15, and day 30
💤 Sleep Quality
- Index I: ↓ 50% at day 15, ↓ 57% at day 30
- Index II: ↓ 55% at midpoint, ↓ 64% at final
😊 Mood & Stress
- Anxiety: ↓ 38% at midpoint, ↓ 3% at final
- Stress: ↓ 43% at midpoint, back to baseline at final
- Depression: Increased ×2 from baseline and remained elevated
⚡ Fatigue
- Total fatigue: ↓ 40% at midpoint, ↓ 60% at final
- Physical fatigue: ↓ 33% at midpoint, ↓ 75% at final
- Mental fatigue: ↓ 50% at midpoint, ↓ 38% at final
💪 Functional & Daily Life
- Physical function: Unchanged at midpoint, ↑ 19% at final
- PROMIS fatigue: No change at midpoint, ↓ 5% at final
- Sleep disturbance: ↓ 22% at midpoint, ↓ 43% at final
- Social participation: ↑ 4% at midpoint, ↓ 3% at final
- Pain interference: ↓ 16% at midpoint, ↑ 5% at final
- Pain score: Stable at midpoint, ↓ 33% at final
🧠 Cerebral Blood Flow
- Regional cerebral oxygenation (rCBO₂): ↑ 2%
- Cerebral blood flow (CBF): ↑ 88%
Key Takeaways
After one month of daily NanoVi Exo® use, C.S. experienced:
- Significant sleep quality improvements
- Marked fatigue reduction
- A substantial increase in cerebral blood flow
- Improved physical function at study end
While depressive symptoms worsened and social participation fluctuated, the strong gains in sleep, fatigue, and neurovascular function point to promising potential for NanoVi Exo® in personalized wellness plans.
Link to full case report: Read full Case Report