Study of NanoVi® Device – Impact on Immune Response
University of Vienna, Center for Sports Science
Abstract
Research conducted at the Center for Sports Science at the University of Vienna evaluated inflammatory markers after exercise-induced oxidative stress. Researchers addressed the question: “What is the impact of inhalation from the NanoVi® device on regenerative capacity –measured by changes to the redox balance in terms of how the immune system responds following an intensive training session?“ The results outlined below describe the impact on white blood cells.
Objective: To assess the effects of NanoVi® bio-identical signaling on blood markers related to immune response and oxidative stress.
Methods: A double-blind, crossover study was conducted with 21 healthy male athletes. Researchers and participants were blinded to the activation status of the NanoVi® device. Diet, supplementation, and exercise were controlled. Testing involved two 15-minute NanoVi® Pro sessions (half the standard session time). Leukocytes and the subcomponents Granulocytes, Monocytes and Lymphocytes were measured as indicators of regeneration associated with immune response. GSH/GSSG ratio was measured as an indicator of oxidative stress. Hematocrit and Hemoglobin levels were measured to reveal the oxygen carrying capacity of the blood. A p-value of 0.05 was required for results to be considered statistically significant.
Venous blood samples were collected at five time points:
- t-30: Before the first NanoVi® session
- t0: After the first NanoVi® session (pre-exertion)
- t55: After the all-out exertion test
- t85: After the second NanoVi® session
- t205: Two hours after the second session
Results: The active NanoVi® group had significantly higher Leukocyte (+10.3%, p=0.03), Granulocyte (+14.0%, p=0.02), and Monocyte (+16.9%, p=0.02) levels at t85, following exertion and the second NanoVi® session. Lymphocyte levels showed no significant differences. Also, GSH/GSSG ratio, Hemoglobin, and Hematocrit levels did not show statistically significant differences, though individual variations were observed. Conclusion: This study supports the regenerative potential of NanoVi® technology. A single 15-minute pre-exertion session influenced immune response, and a second session post-exertion significantly enhanced white blood cell counts. These findings suggest that NanoVi® may aid recovery and support immune resilience following intense physical activity.
