Highlights
- University of Vienna researchers found that athletes using NanoVi® showed increased white blood cell counts after intense exercise.
- Leukocytes, Granulocytes, and Monocytes rose by 10–17%, suggesting enhanced immune response and recovery potential.
- A 15-minute session before and after exercise was enough to produce measurable changes.
- Findings point to NanoVi®’s potential to support immune resilience and post-exercise regeneration naturally and non-invasively.
Can short NanoVi® sessions help the immune system recover after intense exercise?
A research team from the Center for Sports Science at the University of Vienna set out to explore this question, investigating how NanoVi® technology may influence immune and oxidative stress markers following high-intensity physical exertion.
Why It Matters
Strenuous exercise pushes the body beyond its comfort zone. While this is key for performance gains, it also creates oxidative stress — a temporary imbalance that challenges the immune system. Supporting recovery at the cellular level helps athletes bounce back faster and maintain consistent performance.
Study Design
In this double-blind, crossover study, 21 healthy male athletes participated in two 15-minute sessions with the NanoVi® Pro device — one before and one after an all-out exertion test.
Researchers and participants were blinded to the activation status of the device, and diet, supplementation, and exercise conditions were carefully controlled.
Blood samples were collected at five time points to evaluate:
- Immune markers: Leukocytes, Granulocytes, Monocytes, Lymphocytes
- Oxidative stress balance: GSH/GSSG ratio
- Oxygen transport capacity: Hemoglobin and Hematocrit.
Results
Compared to the placebo condition, the active NanoVi® group showed notable differences in key immune parameters after exercise (t85):
- Leukocytes: +10.3% (p=0.03)
- Granulocytes: +14.0% (p=0.02)
- Monocytes: +16.9% (p=0.02)
These increases indicate stronger immune activation and recovery potential following strenuous activity. No significant changes were observed for lymphocytes, oxidative stress markers (GSH/GSSG), or oxygen transport measures, although individual variability was present.
Interpretation
The researchers concluded that even a single 15-minute NanoVi® session before exercise influenced immune parameters, while a second session after exercise further enhanced white blood cell counts. Together, these effects point to improved immune resilience and better physiological recovery following intense exertion.
Why This Is Important for Athletes
A balanced immune system is essential for athletes under heavy training loads. The results from this University of Vienna study suggest that incorporating brief NanoVi® sessions pre- and post-workout may help the body adapt to stress more efficiently — supporting faster recovery, immune balance, and sustained performance over time.
This study was conducted using the NanoVi Pro® device, manufactured by Eng3 Corporation
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Figure 1. Changes in Leukocyte Count Following Exercise With and Without NanoVi® Use. Leukocyte levels increased in both groups following intense exercise; however, athletes who used the NanoVi® device before and after exertion showed a greater rise in total white blood cells (+10.3%) compared to the placebo condition. Measurements were taken over time, with the final reading (t85) showing significantly higher leukocyte counts in the NanoVi® group.
Figure 2. Changes in Granulocyte Count Following Exercise With and Without NanoVi® Use. Granulocyte levels rose progressively after the exertion test in both groups, but participants who used the NanoVi® device showed a greater post-exercise increase (+14.0%) compared to placebo. The difference was most notable at the final measurement (t85), suggesting enhanced immune activation and recovery in the NanoVi® condition.
Figure 3. Changes in Monocyte Count Following Exercise With and Without NanoVi® Use. Monocyte levels increased following intense physical exertion in both groups; however, participants using the NanoVi® device demonstrated a greater post-exercise rise (+16.9%) compared to the placebo condition. The higher monocyte count observed at the final measurement (t85) indicates enhanced immune responsiveness and recovery potential in the NanoVi® group.
Link to full paper: Read here